KARACHI: Cutting-edge stem cell and regenerative research is reshaping the future of medicine, offering new hope to patients and opening pathways for medical innovation in Pakistan. At Aga Khan University (AKU), researchers and clinicians are advancing work that aims to move health care beyond managing illness toward restoring health and improving quality of life.
Stem cell research lies at the heart of regenerative medicine, a field focused on repairing or replacing damaged tissues rather than only treating symptoms. Around the world, this approach is transforming how serious and complex diseases are studied and managed, with growing emphasis on recovery and long-term patient outcomes. These advances are especially significant for people living with chronic or life-limiting conditions, where existing treatment options often remain limited.
Some forms of stem cell therapy are already part of routine medical practice globally, such as bone marrow transplantation for blood cancers and inherited disorders. At the same time, new stem cell-based approaches are progressing through clinical research for a range of conditions, highlighting the importance of careful testing, regulation, and patient safety.
Experts at AKU are focused on research that is both scientifically advanced and relevant to local health needs.
“Our focus is on research that has real meaning for patients,” said Dr Syed Ather Enam, Professor & Director at Centre for Regenerative Medicine, AKU. “By aligning our work with global scientific advances while addressing regional health priorities, we aim to generate knowledge that can ultimately improve care in Pakistan.”
Advancing stem cell research in low-income settings, however, comes with challenges. These include limited resources, infrastructure gaps, and the need for sustained investment over time. AKU is addressing these barriers through capacity building, interdisciplinary collaboration, researcher training, and partnerships that strengthen local expertise rather than relying solely on imported solutions.
“Sustained support for research is essential,” said Dr Azhar Hussain, Assistant Professor at Centre for Regenerative Medicine, AKU. “Breakthroughs do not happen overnight. By investing in people, systems, and ethical research practices, we can overcome constraints and create lasting impact.”
With a long-term vision for regenerative medicine, Aga Khan University aims to build sustainable research capacity, contribute to global scientific progress, and support the gradual development of life-changing therapies that are safe, equitable, and relevant to Pakistan’s health care needs.
